How often do you hear or find yourself wondering what is the difference between an heirloom and an open-pollinated seed variety, an F-1 hybrid and a “GMO?” Misconceptions about these terms are rampant. Breeding techniques continue to evolve, and the ethical debate on the long-term effects of this brave new world of hi-tech breeding will rage on. One concrete way we as seed gardening professionals can help is by providing clarity. Consider this a plain-language “go-to” resource. It will help set the record straight the next time someone refers to the “GMO Food Agenda” or asks the question, “Which is better, an heirloom or a hybrid?” Seed choices abound, and gardeners deserve to make educated decisions about what is best for their own use.